PUBLICATION V53

Equine Immune-Mediated Keratitis (IMMK) FAQs

Publish Date: April 14 2026 |  Language: English

DOI: doi.org/10.7290/UTIAPub/V53

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Summary

Equine immune‑mediated keratitis (IMMK) is a condition in which the horse’s immune system causes inflammation of the cornea. The cornea is the clear front surface of the eye, and inflammation may result in cloudiness, swelling, tearing, squinting, and redness. The severity of IMMK varies widely: some horses have mild disease, while others develop significant discomfort, corneal scarring, vision impairment, or secondary ulcers. Long‑term use of topical steroids may also lead to infections or mineral deposits. Treatment focuses on reducing inflammation and discomfort using topical anti‑inflammatories and immunomodulators such as cyclosporine or tacrolimus, with oral medications in some cases. Management is highly individualized and often lifelong, as IMMK is controllable but not curable. Stress can trigger flare‑ups, so pre‑treatment during stressful events and UV‑protective fly masks are recommended. Surgery is rarely used and reserved for severe cases.